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CS-W001157 4
Total: USD 88.00

5-Bromobenzo[d][1,3]dioxole-4-carbaldehyde

  • CAS No. 72744-54-8

  • Cat. No. CS-0099708
  • Purity≥97%
  • MDL No.MFCD02069012

*For research and further manufacturing use only, not for direct human use.

5-Bromobenzo[d][1,3]dioxole-4-carbaldehyde|CS-0099708

Structure of 72744-54-8

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General Information

  • CAS No. 72744-54-8
  • Cat. No. CS-0099708
  • Purity ≥97%
  • MDL No. MFCD02069012
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrO₃
  • Molecular Weight 229.03
  • Synonym(s) 5-Bromo-1,3-benzodioxole-4-carboxaldehyde
  • SMILES O=CC1=C2OCOC2=CC=C1Br

Description

5-Bromobenzo[d][1,3]dioxole-4-carbaldehyde features a brominated benzodioxole core paired with a reactive aldehyde handle, enabling direct incorporation into Suzuki-Miyaura couplings and other cross-coupling protocols. The electron-deficient aromatic system enhances electrophilicity at the carbonyl carbon, while the bench-stable dioxole ring ensures reliable handling under standard conditions.

Synthesis

  • Route1
    • In-stock
      5-Bromo-1,3-benzodioxole|CS-W008826
      2635-13-4
    • null|null
      68-12-2
    • ~93%
    • In-stock
      5-Bromobenzo[d][1,3]dioxole-4-carbaldehyde|CS-0099708
      72744-54-8

    References

    • Qureshi, Zafar; Weinstabl, Harald; Suhartono, Marcel; Liu, Hongqiang; Thesmar, Pierre; Lautens, Mark European Journal of Organic Chemistry, 2014 , vol. 2014, # 19 p. 4053 - 4069
  • Route2
    • 6-Bromo-2,3-dihydroxybenzaldehyde|CS-0971261
      83983-71-5
    • null|null
      74-95-3
    • ~73%
    • In-stock
      5-Bromobenzo[d][1,3]dioxole-4-carbaldehyde|CS-0099708
      72744-54-8

    References

    • Smidrkal, Jan Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2140 - 2144
  • Route3

    References

    • Collection of Czechoslovak Chemical Communications, , vol. 47, # 8 p. 2140 - 2144

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   1.9903
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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