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CS-W001157 4
Total: USD 88.00

(2-Bromoethyl)triphenylphosphonium bromide

  • CAS No. 7301-93-1

  • Cat. No. CS-0156592
  • Molecule weight450.15
  • Purity≥97%
  • MDL No.MFCD04039352

*For research and further manufacturing use only, not for direct human use.

(2-Bromoethyl)triphenylphosphonium bromide|CS-0156592

Structure of 7301-93-1

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General Information

  • CAS No. 7301-93-1
  • Cat. No. CS-0156592
  • Purity ≥97%
  • MDL No. MFCD04039352
  • Storage RT, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₉Br₂P
  • Molecular Weight 450.15
  • Synonym(s) (2-Bromoethyl)triphenylphosohonium bromide
  • SMILES C1=CC=C(C=C1)[P+](CCBr)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Description

Thalidomide-O-amido-C4-N3 is a functionalized cereblon ligand for PROTAC research, this compound incorporates an E3 ligase ligand in addition to an alkyl C4 linker and a terminal azide. This product is ready for click activated conjugation to target proteins for PROTAC R&D. Please contact us for GMP-grade inquiries.

Synthesis

  • Route1
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      603-35-0
    • ~%
    • (2-Bromoethyl)triphenylphosphonium bromide|CS-0156592
      7301-93-1

    References

    • Seyferth,D.; Fogel,J. Journal of Organometallic Chemistry, 1966 , vol. 6, p. 205 - 227
  • Route2
    • null|null
      106-93-4
    • null|null
      603-35-0
    • ~61%
    • (2-Bromoethyl)triphenylphosphonium bromide|CS-0156592
      7301-93-1

    References

    • Dantas, T. N. de Castro; Laval, J. P.; Lattes, A. Phosphorus and Sulfur and the Related Elements, 1982 , vol. 13, p. 97 - 106
  • Route3

    References

    • Seyferth,D.; Fogel,J. Journal of Organometallic Chemistry, 1966 , vol. 6, p. 205 - 227

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   1.3794
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   5

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