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CS-W001157 4
Total: USD 88.00

(S)-4-Hydroxydihydrofuran-2(3H)-one

  • CAS No. 7331-52-4

  • Cat. No. CS-W013702
  • Molecule weight102.09
  • Purity≥85%
  • MDL No.MFCD00211247

*For research and further manufacturing use only, not for direct human use.

(S)-4-Hydroxydihydrofuran-2(3H)-one|CS-W013702

Structure of 7331-52-4

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General Information

  • CAS No. 7331-52-4
  • Cat. No. CS-W013702
  • Purity ≥85%
  • MDL No. MFCD00211247
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆O₃
  • Molecular Weight 102.09
  • Synonym(s) (S)-3-Hydroxy-gamma-butyrolactone
  • SMILES O=C1OC[C@@H](O)C1

Description

(S)-4-Hydroxydihydrofuran-2(3H)-one is a chiral heterocyclic building block featuring a hydroxyl group at C4 and a lactone carbonyl at C2. This scaffold exhibits enhanced stability under standard bench conditions, enabling reliable incorporation into complex molecular architectures. Its defined stereochemistry facilitates stereoselective transformations in synthetic pathways.

Application

(S)-4-Hydroxydihydrofuran-2(3H)-one serves as a versatile chiral building block for the synthesis of bioactive heterocycles and natural product analogs. Its enantiopure structure enables stereoselective transformations in medicinal chemistry, particularly in the construction of oxetane and tetrahydrofuran scaffolds. The molecule exhibits bench stability, facilitates efficient functionalization at C-4, and is compatible with standard protecting group strategies and coupling protocols used in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   -0.7058
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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