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CS-W001157 4
Total: USD 88.00

4-(Hydroxymethyl)phenylacetic acid

  • CAS No. 73401-74-8

  • Cat. No. CS-W004128
  • Purity≥97%
  • MDL No.MFCD00065692
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(Hydroxymethyl)phenylacetic acid|CS-W004128

Structure of 73401-74-8

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Description

4-(Hydroxymethyl)phenylacetic acid features a hydroxymethyl group flanking a phenylacetic core, enabling facile derivatization and integration into bioconjugation workflows. This bench-stable, moisture-tolerant reagent delivers enhanced solubility in aqueous-organic mixtures, streamlining purification and handling during synthetic and analytical applications.

Application

4-(Hydroxymethyl)phenylacetic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive molecules via established coupling and functional group transformation protocols. Its phenylacetic core provides structural rigidity and metabolic stability, while the pendant hydroxymethyl group offers a handle for derivatization—facilitating conjugation, protection, or further functionalization. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis workflows in API development.

General Information

  • CAS No. 73401-74-8
  • Cat. No. CS-W004128
  • Purity ≥97%
  • MDL No. MFCD00065692
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.18
  • Synonym(s) 4HMPAA
  • SMILES O=C(CC1=CC=C(CO)C=C1)O

Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.806
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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