Propiolamide

Name: Propiolamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 7341-96-0
Cat. No. CS-0022393
Purity≥97%
MDL No.MFCD04035573

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HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 7341-96-0

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Description

Propiolamide delivers a reactive terminal alkyne functionality paired with a stable amide group, enabling direct incorporation into conjugation workflows. This bifunctional scaffold supports efficient coupling under mild conditions, facilitating rapid access to diverse molecular architectures in synthetic and medicinal chemistry applications.

Application

Propiolamide serves as a versatile building block in synthetic organic chemistry, enabling efficient access to α,β-unsaturated amides and heterocyclic scaffolds via cyclization or conjugate addition reactions. Its terminal alkyne and amide functionalities offer orthogonal reactivity, facilitating Cu-catalyzed coupling and functional group transformations under mild conditions. Bench-stable and readily purified by distillation or chromatography, it supports scalable synthesis of complex molecular architectures in medicinal chemistry and materials science applications.

General Information

CAS No. 7341-96-0
Cat. No. CS-0022393
Purity ≥97%
MDL No. MFCD04035573
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₃NO
Molecular Weight 69.06
Synonym(s) None
SMILES O=C(C#C)N

Computational Chemistry Data

TPSA 43.09
LogP -0.8951
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Fatty chain compounds

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Terminal Alkynes

Key Words

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Propiolamide

CAS No. 7341-96-0

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