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Structure of 737000-76-9
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3,5-Difluoro-2-methoxybenzeneboronic acid features a boronate moiety flanked by two fluorine atoms and a methoxy group, enabling efficient Suzuki-Miyaura coupling under mild conditions. This electron-deficient arylboronic acid exhibits enhanced stability and solubility in polar solvents, facilitating reliable cross-coupling reactions in complex molecule synthesis.
3,5-Difluoro-2-methoxybenzeneboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced metabolic stability. The ortho-methoxy group provides steric and electronic modulation, while the difluoro substitution enhances both solubility and resistance to protodeboronation. Bench-stable and readily purified by recrystallization, it functions reliably in diverse reaction conditions, facilitating access to complex aromatic architectures common in pharmaceutical discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: