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Structure of 7379-35-3
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4-Chloropyridine (hydrochloride) offers a stable, moisture-tolerant platform for pyridine-based synthesis. The protonated nitrogen enhances electrophilic reactivity, while the para-chloro substituent enables direct functionalization via cross-coupling or nucleophilic substitution. This salt form improves solubility in polar solvents and simplifies handling under standard bench conditions.
4-Chloropyridine (hydrochloride) serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient nucleophilic substitution reactions at the pyridine C4 position. Its protonated form enhances solubility and stability in aqueous and polar organic media, facilitating handling and purification. The chloride functionality permits reliable coupling with amines, thiols, and organometallic reagents, supporting the construction of heterocyclic scaffolds and functionalized intermediates under standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: