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Structure of 73790-05-3
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Ethyl 2-(3,4-difluorophenyl)-2-oxoacetate is a bench-stable, moisture-tolerant ketone precursor featuring a sterically accessible β-ketoester moiety. The para-fluorinated aryl group enhances electron deficiency, enabling efficient coupling in transition-metal-catalyzed C–C bond formations and facilitating downstream functionalization in medicinal chemistry synthesis.
Ethyl 2-(3,4-difluorophenyl)-2-oxoacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of chiral α-hydroxy and α-amino acid derivatives via stereoselective transformations. Its enolizable ketone functionality facilitates aldol and Michael additions, while the difluorophenyl group enhances metabolic stability and modulates electronic properties—valuable for medicinal chemistry applications. The ester moiety supports straightforward derivatization and purification, offering robust bench stability and compatibility with standard reaction conditions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: