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CS-W001157 4
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3-((tert-Butyldimethylsilyl)oxy)propan-1-ol

  • CAS No. 73842-99-6

  • Cat. No. CS-W007946
  • Purity≥96%
  • MDL No.MFCD00187968

*For research and further manufacturing use only, not for direct human use.

3-((tert-Butyldimethylsilyl)oxy)propan-1-ol|CS-W007946

Structure of 73842-99-6

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General Information

  • CAS No. 73842-99-6
  • Cat. No. CS-W007946
  • Purity ≥96%
  • MDL No. MFCD00187968
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₂₂O₂Si
  • Molecular Weight 190.36
  • Synonym(s) None
  • SMILES OCCCO[Si](C)(C)C(C)(C)C

Description

This silyl-protected diol delivers reliable stability and orthogonal functionality in complex synthesis. The tert-butyldimethylsilyl ether group enables selective protection of primary alcohols, while the terminal hydroxyl remains available for further transformation under standard conditions.

Synthesis

  • Route1
    • null|null
      18162-48-6
    • In-stock
      1,3-Propanediol|CS-W018490
      504-63-2
    • ~99%
    • In-stock
      3-((tert-Butyldimethylsilyl)oxy)propan-1-ol|CS-W007946
      73842-99-6

    References

    • UNIVERSITY OF PITTSBURGH Patent: WO2005/117588 A2, 2005 ; Location in patent: Page/Page column 31 ;
  • Route2
    • null|null
      203738-77-6
    • ~92%
    • In-stock
      3-((tert-Butyldimethylsilyl)oxy)propan-1-ol|CS-W007946
      73842-99-6

    References

    • Ikawa, Takashi; Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku Tetrahedron, 2004 , vol. 60, # 32 p. 6901 - 6911
  • Route3
    • null|null
      203738-77-6
    • ~79%
    • In-stock
      3-((tert-Butyldimethylsilyl)oxy)propan-1-ol|CS-W007946
      73842-99-6
    • In-stock
      1,3-Propanediol|CS-W018490
      504-63-2

    References

    • Tetrahedron Letters, , vol. 39, # 51 p. 9461 - 9464

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   2.3906
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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