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Structure of 7385-87-7
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8-Bromonaphthalen-2-ol features a bromine atom at the 8-position of the naphthalene core, paired with a phenolic hydroxyl group at the 2-position. This arrangement imparts enhanced electrophilic reactivity and facilitates coupling reactions under mild conditions. The compound exhibits good stability under standard bench protocols and serves as a key intermediate in the synthesis of functionalized polycyclic systems.
8-Bromonaphthalen-2-ol serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromide functionality. The phenolic hydroxyl group provides a handle for derivatization and enhances solubility, while the naphthalene core offers rigidity and extended π-conjugation. Its bench stability and compatibility with common protecting groups facilitate efficient synthesis of complex heterocycles and functionalized aromatic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: