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Structure of 73852-18-3
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2,4,6-Trichlorophenylboronic acid features a boronic acid group flanked by three chlorine atoms at the 2, 4, and 6 positions of the phenyl ring. This electron-deficient arylboronic acid exhibits enhanced stability and reactivity in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. The trichloro substitution improves solubility in organic solvents and facilitates handling in synthetic workflows.
2,4,6-Trichlorophenylboronic acid serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its electron-deficient aryl boronic acid functionality enables efficient coupling with diverse halides and pseudohalides under mild conditions. The three ortho-chlorine substituents enhance reactivity while maintaining compatibility with common protecting groups and functional group tolerances. This compound facilitates rapid access to substituted biaryls and complex heterocyclic scaffolds in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: