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Structure of 7397-68-4
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1H-Imidazo[4,5-c]pyridin-2(3H)-one is a heterocyclic scaffold featuring a fused imidazole-pyridine core with intrinsic electron-deficient character. This rigid, planar structure enhances π-stacking interactions and confers stability under standard conditions. The lactam functionality enables hydrogen bonding and facilitates incorporation into bioactive molecules. It serves as a privileged motif in medicinal chemistry for targeting protein-protein interactions and kinase inhibition.
1H-Imidazo[4,5-c]pyridin-2(3H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its fused tricyclic structure exhibits robust bench stability and facilitates diverse functionalization at the C1, C4, and C7 positions. The compound functions effectively in transition-metal-catalyzed coupling reactions and serves as a key intermediate in the synthesis of kinase inhibitors and other pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: