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Structure of 73998-96-6
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2,4-Dichloro-5-(chloromethyl)pyridine features a pyridine core with dual chloro substituents at the 2- and 4-positions and a reactive chloromethyl group at the 5-position. This trifunctional architecture enables direct coupling in nucleophilic substitution reactions, facilitating rapid integration into complex molecular scaffolds. The electron-deficient ring enhances reactivity toward amines and thiols under mild conditions. The chloromethyl moiety serves as a site for further functionalization, enabling modular synthesis of bioactive compounds.
2,4-Dichloro-5-(chloromethyl)pyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis. The chloromethyl group enables efficient functionalization via nucleophilic substitution, while the pyridine core provides a handle for transition-metal-catalyzed coupling reactions. Its bench-stable nature and compatibility with diverse reaction conditions facilitate rapid diversification of heterocyclic scaffolds in API development workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: