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Structure of 7401-98-1
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2,4-Dichloro-5-(methylthio)pyrimidine serves as a key heterocyclic scaffold in medicinal chemistry, featuring two chlorine substituents at electron-rich positions and a methylthio group that enhances lipophilicity and metabolic stability. This combination enables efficient coupling in cross-coupling reactions, facilitating rapid access to complex pyrimidine derivatives for drug discovery applications.
2,4-Dichloro-5-(methylthio)pyrimidine serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyrimidines via nucleophilic displacement. The dichloro functionality facilitates sequential functionalization at C2 and C4 positions, while the methylthio group offers a stable, orthogonal handle for further modification. Its bench-stable nature and compatibility with standard coupling conditions make it well-suited for medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P305+P351+P338-P330-P501
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Lot numbers can be found on the outside label of a product: