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Structure of 7405-23-4
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4-Hydroxybenzothiazole features a hydroxyl group conjugated to an electron-deficient benzothiazole core, enabling robust hydrogen bonding and enhanced solubility in polar solvents. This structural motif facilitates integration into bioactive scaffolds and functional materials.
4-Hydroxybenzothiazole serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the phenolic hydroxyl group. Its stability under standard reaction conditions facilitates coupling reactions, including Suzuki-Miyaura and Ullmann-type transformations, while the benzothiazole core provides enhanced metabolic stability and π-stacking capability in bioactive scaffolds. The compound functions effectively as a synthetically accessible precursor for heterocyclic libraries and exhibits favorable purification characteristics via recrystallization or silica chromatography.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: