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Structure of 741288-57-3
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1,3,3-Trimethylpiperazine is a sterically hindered, bench-stable piperazine derivative featuring three methyl groups that enhance solubility and reduce nucleophilicity. This configuration imparts high stability under standard conditions while maintaining reactivity in amine coupling and catalyst ligand applications.
1,3,3-Trimethylpiperazine serves as a versatile nitrogen-containing scaffold in medicinal chemistry, offering enhanced metabolic stability and improved solubility profiles. Its tertiary amine functionality enables efficient salt formation and facilitates interactions with biological targets. The molecule demonstrates excellent bench stability and compatibility with standard coupling reactions, making it a practical building block for fragment-based drug discovery and the synthesis of complex heterocyclic systems.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: