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Structure of 7425-53-8
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Ethyl γ-iodobutyrate is a versatile alkylating agent featuring a reactive iodide group at the γ-position. This configuration enables efficient carbon–carbon bond formation in transition-metal-catalyzed cross-coupling reactions. The ester functionality enhances solubility in organic solvents and supports compatibility with diverse reaction conditions. Its bench-stable nature facilitates handling under standard laboratory protocols.
Ethyl γ-iodobutyrate serves as a versatile γ-halo ester building block for transition-metal-catalyzed coupling reactions. Its iodide functionality enables efficient Pd- or Ni-mediated cross-couplings, including Negishi and Suzuki-Miyaura variants, with broad functional group tolerance. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of complex alkylated scaffolds in medicinal chemistry and process development workflows.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: