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CS-W001157 4
Total: USD 88.00

Methyl(naphthalen-2-yl)sulfane

  • CAS No. 7433-79-6

  • Cat. No. CS-0368258
  • Molecule weight174.26
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl(naphthalen-2-yl)sulfane|CS-0368258

Structure of 7433-79-6

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General Information

  • CAS No. 7433-79-6
  • Cat. No. CS-0368258
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₀S
  • Molecular Weight 174.26
  • Synonym(s) 2-(Methylthio)naphthalene
  • SMILES CSC1=CC2=CC=CC=C2C=C1

Description

Methyl(naphthalen-2-yl)sulfane features a sulfane linkage between methyl and naphthalen-2-yl moieties, delivering a robust, moisture-tolerant scaffold. This compound integrates readily into synthetic sequences requiring stable sulfur-directed functionalization. The aromatic naphthalene core enhances π-stacking potential in molecular assembly contexts.

Application

Methyl(naphthalen-2-yl)sulfane serves as a stable, bench-ready sulfide building block for transition-metal-catalyzed cross-coupling reactions. Its naphthyl moiety provides a rigid, hydrophobic scaffold useful in medicinal chemistry and materials science. The methylthio group enables selective oxidation to sulfoxides or sulfones under controlled conditions, facilitating functional group interconversion. This compound exhibits good solubility in common organic solvents and tolerates a range of reaction conditions, making it suitable for iterative synthesis workflows.

Synthesis

  • Route1

    References

    • Zhang, Jianghua; Gao, Xinqin; Zhang, Chengyi; Zhang, Cheng; Luan, Jiming; Zhao, Defeng Synthetic Communications, 2010 , vol. 40, # 12 p. 1794 - 1801
  • Route2

    References

    • Luo, Fang; Pan, Changduo; Li, Liping; Chen, Fan; Cheng, Jiang Chemical Communications, 2011 , vol. 47, # 18 p. 5304 - 5306
  • Route3
    • null|null
      67-56-1
    • null|null
      89781-11-3
    • ~10%
    • null|null
      107-31-3
    • In-stock
      Methyl(naphthalen-2-yl)sulfane|CS-0368258
      7433-79-6

    References

    • Bott, Kaspar Chemische Berichte, 1993 , vol. 126, # 8 p. 1955 - 1956

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H319-H372-H410
Precautionary Statements : P260-P264-P270-P273-P280-P330-P391-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.5617
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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