1H-Pyrrolo[2,3-b]pyridin-4-ol

Name: 1H-Pyrrolo[2,3-b]pyridin-4-ol
Brand: ChemScene
Availability: InStock
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CAS No. 74420-02-3
Cat. No. CS-B0509
Purity≥98%
MDL No.MFCD08272229

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 74420-02-3

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Description

1H-Pyrrolo[2,3-b]pyridin-4-ol features a fused heterocyclic core with a phenolic hydroxyl group enabling hydrogen bonding and enhanced solubility. This scaffold integrates readily into bioactive molecules, offering structural rigidity and electron-rich character ideal for medicinal chemistry applications.

Application

1H-Pyrrolo[2,3-b]pyridin-4-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of advanced scaffolds through established coupling and functionalization reactions. Its inherent stability and compatibility with diverse reaction conditions facilitate efficient access to bioactive molecules. The hydroxyl group provides a handle for derivatization, while the fused ring system offers defined rigidity and π-conjugation, enhancing target selectivity in drug discovery applications.

General Information

CAS No. 74420-02-3
Cat. No. CS-B0509
Purity ≥98%
MDL No. MFCD08272229
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆N₂O
Molecular Weight 134.14
Synonym(s) 7-H-PYRROLO [2-3-B] PYRIDINE-4-OL
SMILES OC1=C2C(NC=C2)=NC=C1

Computational Chemistry Data

TPSA 48.91
LogP 1.2685
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Key Words

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1H-Pyrrolo[2,3-b]pyridin-4-ol

CAS No. 74420-02-3

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