5,7-Dichlorothieno[3,2-b]pyridine

Name: 5,7-Dichlorothieno[3,2-b]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 74695-44-6
Cat. No. CS-0019303
Purity≥98%
MDL No.MFCD09953620

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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5,7-Dichlorothieno[3,2-b]pyridine|CS-0019303

Structure of 74695-44-6

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Description

5,7-Dichlorothieno[3,2-b]pyridine is a heterocyclic scaffold featuring two chlorine substituents at the 5 and 7 positions, enhancing electron deficiency and enabling robust coupling reactions. This bench-stable core integrates readily into advanced synthetic architectures for pharmaceuticals and functional materials.

Application

5,7-Dichlorothieno[3,2-b]pyridine serves as a versatile heterocyclic building block in medicinal chemistry and materials science. Its dual chlorine substituents enable selective cross-coupling reactions, facilitating the construction of complex scaffolds under palladium-catalyzed conditions. The molecule exhibits excellent bench stability and compatibility with standard functional groups, making it well-suited for iterative synthesis workflows and scale-up applications.

General Information

CAS No. 74695-44-6
Cat. No. CS-0019303
Purity ≥98%
MDL No. MFCD09953620
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₃Cl₂NS
Molecular Weight 204.08
Synonym(s) 5,7-dichlorothienopyridine
SMILES ClC1=C2C(C=CS2)=NC(Cl)=C1

Computational Chemistry Data

TPSA 12.89
LogP 3.6031
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

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5,7-Dichlorothieno[3,2-b]pyridine

CAS No. 74695-44-6

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