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Structure of 74733-25-8
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Methyl 3-fluoro-4-formylbenzoate features a fluorinated aromatic ring with complementary formyl and ester functionalities, enabling direct integration into Suzuki-Miyaura couplings and multicomponent condensations. The electron-deficient formyl group facilitates nucleophilic addition, while the methyl ester offers stability under standard conditions. This compound serves as a key building block in the synthesis of bioactive heterocycles and functionalized pharmaceutical intermediates.
Methyl 3-fluoro-4-formylbenzoate serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling efficient access to fluorinated aromatic scaffolds. The formyl group facilitates nucleophilic additions, condensations, and cyclizations, while the methyl ester provides a handle for selective transformations. Its ortho-fluoro substituent enhances metabolic stability and modulates electronic properties, offering predictable reactivity in standard coupling and functionalization protocols. Bench-stable and readily purified by chromatography, it functions effectively in multi-step syntheses of bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: