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Structure of 74844-93-2
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This chiral pyrrolidine diester features a sterically hindered tert-butyl group and a methyl substituent at the 2-position, enabling high stereoselectivity in asymmetric synthesis. The electron-deficient pyrroline core facilitates efficient coupling reactions, while the bench-stable, moisture-tolerant structure simplifies handling in process development workflows.
1-(tert-Butyl) 2-methyl (S)-2,5-dihydro-1H-pyrrole-1,2-dicarboxylate serves as a stable, bench-ready chiral building block for synthesizing pyrrolidine-containing scaffolds. Its (S)-configuration and protected diester functionality enable stereoselective transformations, including hydrogenation and nucleophilic substitution. The tert-butyl and methyl groups enhance solubility and facilitate purification, making it ideal for iterative synthesis in medicinal chemistry and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: