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8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one

  • CAS No. 74904-29-3

  • Cat. No. CS-0569467
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one|CS-0569467

Structure of 74904-29-3

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General Information

  • CAS No. 74904-29-3
  • Cat. No. CS-0569467
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₁NO₂
  • Molecular Weight 177.20
  • Synonym(s) 3,4-dihydro-8-Methoxyisoquinolin-1(2H)-one
  • SMILES COC1=CC=CC2=C1C(=O)NCC2

Synthesis

  • Route1

    References

    • Jesudason, Cynthia D.; Beavers, Lisa S.; Cramer, Jeffrey W.; Dill, Joelle; Finley, Don R.; Lindsley, Craig W.; Stevens, F. Craig; Gadski, Robert A.; Oldham, Samuel W.; Pickard, R. Todd; Siedem, Christopher S.; Sindelar, Dana K.; Singh, Ajay; Watson, Brian M.; Hipskind, Philip A. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 13 p. 3415 - 3418
  • Route2

    References

    • Sall; Grunewald Journal of Medicinal Chemistry, 1987 , vol. 30, # 12 p. 2208 - 2216
  • Route3
    • null|null
      110192-21-7
    • ~8%
    • 8-Methoxy-3,4-dihydroisoquinolin-1(2H)-one|CS-0569467
      74904-29-3

    References

    • SCHERING CORPORATION; PHARMACOPEIA DRUG DISCOVERY, INC. Patent: WO2005/68460 A1, 2005 ; Location in patent: Page/Page column 330 ; WO 2005/068460 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.9811
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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