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Structure of 749269-74-7
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This cyclopropanecarboxylic acid features a 4-bromo-3-fluorophenyl substituent, delivering enhanced metabolic stability and favorable lipophilicity for medicinal chemistry applications. The strained cyclopropyl ring imparts conformational rigidity, enabling precise spatial orientation in target binding. This derivative integrates readily into bioactive scaffolds requiring electron-deficient aryl motifs.
1-(4-Bromo-3-fluorophenyl)cyclopropanecarboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its cyclopropane carboxylic acid motif provides structural rigidity and enhanced metabolic stability, while the ortho-bromo and meta-fluoro substituents enable palladium-catalyzed cross-coupling reactions and modulate electronic properties. The carboxylic acid group facilitates direct derivatization or salt formation, supporting purification and handling in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: