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CS-W001157 4
Total: USD 88.00

1H-Indene-2-boronic acid pinacol ester

  • CAS No. 749869-98-5

  • Cat. No. CS-0342190
  • Molecule weight242.12
  • Purity≥97%
  • MDL No.MFCD11506072

*For research and further manufacturing use only, not for direct human use.

1H-Indene-2-boronic acid pinacol ester|CS-0342190

Structure of 749869-98-5

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General Information

  • CAS No. 749869-98-5
  • Cat. No. CS-0342190
  • Purity ≥97%
  • MDL No. MFCD11506072
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₉BO₂
  • Molecular Weight 242.12
  • Synonym(s) 2-(1H-Inden-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • SMILES CC1(C)C(C)(C)OB(C2=CC3=CC=CC=C3C2)O1

Description

1H-Indene-2-boronic acid pinacol ester offers a stable, bench-ready boronate handle for Suzuki-Miyaura cross-coupling reactions. The pinacol ester protects the boronic acid functionality, enhancing shelf life and handling safety while enabling efficient C–C bond formation under mild conditions. This derivative integrates seamlessly into complex molecular architectures.

Application

1H-Indene-2-boronic acid pinacol ester serves as a stable, bench-ready building block for Suzuki-Miyaura cross-coupling reactions. Its robust boronate ester functionality enables reliable C–C bond formation under mild conditions, with excellent functional group tolerance and ease of purification. The indene core provides a rigid, aromatic scaffold valuable in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   3.2575
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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