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CS-W001157 4
Total: USD 88.00

(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid

  • CAS No. 7536-58-5

  • Cat. No. CS-0020431
  • Molecule weight323.34
  • Purity≥98%
  • MDL No.MFCD00065564

*For research and further manufacturing use only, not for direct human use.

(2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid|CS-0020431

Structure of 7536-58-5

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General Information

  • CAS No. 7536-58-5
  • Cat. No. CS-0020431
  • Purity ≥98%
  • MDL No. MFCD00065564
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₁NO₆
  • Molecular Weight 323.34
  • Synonym(s) Boc-L-Asp(OBn)-OH
  • SMILES O=C(OCC1=CC=CC=C1)C[C@H](NC(OC(C)(C)C)=O)C(O)=O

Description

This (2S)-4-(benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid features a chiral β-amino carbonyl scaffold with orthogonal functional handles: a benzyl ether for temporary protection and a robust tert-butyl carbamate group enabling selective deprotection. The molecule integrates seamlessly into peptide synthesis workflows, offering precise control over side-chain modulation and facilitating the construction of complex peptidomimetics under standard conditions.

Synthesis

  • Route1

    References

    • Tetrahedron Letters, , vol. 32, # 45 p. 6637 - 6640
  • Route2
    • null|null
      149636-02-2
    • ~10%
    • In-stock
      (2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid|CS-0020431
      7536-58-5

    References

    • Tetrahedron Letters, , vol. 34, # 17 p. 2783 - 2786
  • Route3
    • null|null
      130052-03-8
    • ~90%
    • In-stock
      (2S)-4-(Benzyloxy)-2-[(tert-butoxycarbonyl)amino]-4-oxobutanoic acid|CS-0020431
      7536-58-5

    References

    • Chemistry of Natural Compounds, , vol. 26, # 2 p. 196 - 198 Khimiya Prirodnykh Soedinenii, , # 2 p. 241 - 245

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   2.0978
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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