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Structure of 7556-37-8
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1-Methyl-1H-indol-4-ol features a methyl-substituted indole core with a phenolic hydroxyl at the 4-position, delivering enhanced solubility and stability compared to unsubstituted analogs. This scaffold integrates readily into bioactive molecule design, offering a robust platform for medicinal chemistry exploration.
1-Methyl-1H-indol-4-ol serves as a versatile building block in medicinal chemistry, enabling direct access to substituted indole scaffolds through electrophilic substitution and cross-coupling reactions. Its phenolic functionality facilitates derivatization while maintaining bench stability, and the methyl group enhances solubility and metabolic resistance. The compound functions effectively in Suzuki-Miyaura and Ullmann-type couplings, supporting efficient synthesis of complex heterocycles and potential API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: