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Structure of 7556-47-0
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6-Methoxyindoline features a methoxy group at the 6-position of the indoline scaffold, enhancing electron density and solubility. This bench-stable compound serves as a key building block in medicinal chemistry, integrating readily into diverse heterocyclic architectures through C–H functionalization or coupling reactions.
6-Methoxyindoline serves as a versatile building block in medicinal chemistry, enabling the construction of biologically relevant heterocyclic scaffolds. Its electron-donating methoxy group enhances solubility and modulates reactivity in electrophilic substitution and transition-metal-catalyzed coupling reactions. The indoline core provides a rigid, planar framework suitable for target-directed synthesis, while the amine functionality offers straightforward derivatization. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step syntheses of kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 2735
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: