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Structure of 75680-92-1
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Ethyl 6-chloro-3-pyridazinecarboxylate features a chlorinated pyridazine core that enables direct functionalization at the C6 position. This electron-deficient heterocycle integrates readily into cross-coupling and nucleophilic substitution reactions, offering high stability under standard conditions. The ester moiety facilitates downstream derivatization while maintaining structural integrity.
Ethyl 6-chloro-3-pyridazinecarboxylate serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted pyridazines via palladium-catalyzed cross-coupling reactions. The chloro group at the 6-position exhibits high reactivity toward nucleophilic substitution, facilitating the installation of diverse aryl, heteroaryl, and alkyl substituents under mild conditions. Its stability under standard bench handling and compatibility with common functional groups make it ideal for modular synthesis of biologically active scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: