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CS-W001157 4
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N1,N3-bis(4-(trifluoromethyl)phenyl)malonamide

  • CAS No. 7574-50-7

  • Cat. No. CS-0552878
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N1,N3-bis(4-(trifluoromethyl)phenyl)malonamide|CS-0552878

Structure of 7574-50-7

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General Information

  • CAS No. 7574-50-7
  • Cat. No. CS-0552878
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₇H₁₂F₆N₂O₂
  • Molecular Weight 390.28
  • Synonym(s) N,N'-bis[4-(trifluoromethyl)phenyl]propanediamide
  • SMILES C1=CC(=CC=C1C(F)(F)F)NC(=O)CC(=O)NC2=CC=C(C=C2)C(F)(F)F

Synthesis

  • Route1
    • 4-(Trifluoromethyl)aniline Leflunomide Impurity|CS-0229655
      455-14-1
    • null|null
      1663-67-8
    • ~94%
    • N1,N3-bis(4-(trifluoromethyl)phenyl)malonamide|CS-0552878
      7574-50-7

    References

    • Bertolini, Giorgio; Aquino, Mario; Biffi, Mauro; D'Atri, Gaetano; Di Pierro, Francesco; Ferrario, Francesco; Mascagni, Paolo; Somenzi, Flavio; Zaliani, Andrea; Leoni, Flavio Journal of Medicinal Chemistry, 1997 , vol. 40, # 13 p. 2011 - 2016

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   58.2
  • LogP   4.6915
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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