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Structure of 757978-18-0
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5-Bromo-3-iodo-7-azaindole features a sterically accessible core with complementary halogen handles enabling efficient cross-coupling. The electron-deficient 7-azaindole scaffold enhances reactivity in Pd-catalyzed transformations, while the bromo and iodo substituents allow sequential functionalization under mild conditions. This dual-halogenated heterocycle serves as a pivotal building block for complex molecular architectures in medicinal chemistry and materials science.
5-Bromo-3-iodo-7-azaindole serves as a versatile building block for the construction of functionalized heterocycles in medicinal chemistry and materials science. The strategic placement of bromo and iodo substituents enables sequential cross-coupling reactions, including Suzuki-Miyaura and Stille couplings, with high chemoselectivity and excellent functional group tolerance. Bench-stable and readily purified by column chromatography, it functions as a key intermediate in the synthesis of complex azaindole-based scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: