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Structure of 75833-38-4
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2-Chloropyrimidine-4-carbonitrile features a reactive chloro group at the 2-position and a strongly electron-withdrawing nitrile at the 4-position, enabling efficient coupling in nucleophilic substitution reactions. This dual functionality supports rapid diversification in heterocyclic synthesis, particularly in pharmaceutical and agrochemical development.
2-Chloropyrimidine-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds through nucleophilic substitution. Its dual functional groups—chlorine at C2 and nitrile at C4—offer orthogonal reactivity for sequential derivatization, with the nitrile group amenable to hydrolysis or reduction under standard conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: