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Structure of 75884-70-7
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6-Bromophthalazinone features a bromine substituent at the 6-position of the phthalazinone core, enabling direct functionalization in cross-coupling reactions. The electron-deficient heterocycle facilitates nucleophilic substitution and serves as a key scaffold for medicinal chemistry applications.
6-Bromophthalazinone serves as a versatile building block in medicinal chemistry and synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig couplings. Its bromine substituent offers high reactivity and compatibility with standard coupling conditions, while the phthalazinone core provides structural rigidity and hydrogen-bonding capacity useful in drug discovery. The compound exhibits excellent bench stability, ease of purification, and functional group tolerance, making it well-suited for iterative synthesis of complex heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: