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CS-W001157 4
Total: USD 88.00

2-(4-Fluorophenyl)ethanol

  • CAS No. 7589-27-7

  • Cat. No. CS-W004152
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD00002898

*For research and further manufacturing use only, not for direct human use.

2-(4-Fluorophenyl)ethanol|CS-W004152

Structure of 7589-27-7

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General Information

  • CAS No. 7589-27-7
  • Cat. No. CS-W004152
  • Purity ≥98%
  • MDL No. MFCD00002898
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉FO
  • Molecular Weight None
  • Synonym(s) 4-fluorophenyl ethanol
  • SMILES FC1=CC=C(CCO)C=C1

Description

4-Fluorophenethyl alcohol was used to prepare 1-fluoro-4-(2-iodoethyl)benzene.

Application

2-(4-Fluorophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard functional group transformations. Its bench-stable nature and compatibility with common coupling reactions facilitate efficient incorporation into pharmaceutical scaffolds. The molecule functions as a key intermediate in the construction of arylalkyl motifs found in CNS-targeted therapeutics and kinase inhibitors.

Synthesis

  • Route1
    • null|null
      405-50-5
    • ~89%
    • In-stock
      2-(4-Fluorophenyl)ethanol|CS-W004152
      7589-27-7

    References

    • Misal Castro, Luis C.; Li, Haoquan; Sortais, Jean-Baptiste; Darcel, Christophe Chemical Communications (Cambridge, United Kingdom), 2012 , vol. 48, # 85 p. 10514 - 10516,3
  • Route2
    • 2-(4-Fluorophenyl)oxirane|CS-0063809
      18511-62-1
    • ~80%
    • In-stock
      2-(4-Fluorophenyl)ethanol|CS-W004152
      7589-27-7

    References

    • Ley, Steven V.; Mitchell, Claire; Pears, David; Ramarao, Chandrashekar; Yu, Jin-Quan; Zhou, Wuzong Organic Letters, 2003 , vol. 5, # 24 p. 4665 - 4668
  • Route3

    References

    • Junge, Kathrin; Wendt, Bianca; Zhou, Shaolin; Beller, Matthias European Journal of Organic Chemistry, 2013 , # 11 p. 2061 - 2065

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302+H312-H315-H319-H335-H412
Precautionary Statements : P264-P270-P271-P280-P261-P273-P301+P312-P302+P352-P330-P362+P364-P305+P351+P338-P305+P351+P338-P304+P340-P332+P313-P405-P403+P233-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.3605
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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