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CS-W001157 4
Total: USD 88.00

2-(4-Fluorophenyl)propanoic acid

  • CAS No. 75908-73-5

  • Cat. No. CS-W002265
  • Purity≥96%
  • MDL No.MFCD00054492
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(4-Fluorophenyl)propanoic acid|CS-W002265

Structure of 75908-73-5

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Description

2-(4-Fluorophenyl)propanoic acid features a fluorinated aromatic ring paired with a chiral aliphatic carboxylic acid moiety, enabling its use in asymmetric synthesis and medicinal chemistry. This bench-stable compound integrates readily into pharmaceutical intermediates requiring electron-withdrawing fluorine substitution and enhanced metabolic stability.

Application

2-(4-Fluorophenyl)propanoic acid serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard coupling and functionalization reactions. Its fluorinated aromatic moiety enhances metabolic stability and modulates lipophilicity, while the α-methyl carboxylic acid functionality offers reliable reactivity in amide bond formation, esterification, and decarboxylation processes. The compound exhibits excellent bench stability and is readily purified by recrystallization, facilitating its use in scalable synthetic routes.

General Information

  • CAS No. 75908-73-5
  • Cat. No. CS-W002265
  • Purity ≥96%
  • MDL No. MFCD00054492
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉FO₂
  • Molecular Weight 168.17
  • Synonym(s) p-Fluoro-ALPHA-methylphenylacetic acid
  • SMILES CC(c1ccc(cc1)F)C(=O)O

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.0138
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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