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Structure of 762263-66-1
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This boronic acid features a phenolic hydroxyl group adjacent to a boronate moiety, enabling direct functionalization in Suzuki-Miyaura couplings. The methyl substituent enhances electron density at the aromatic ring, improving reactivity and stability under standard conditions. Its bench-stable nature simplifies handling in synthetic workflows.
(4-Hydroxy-3-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The ortho-hydroxyl group enhances regioselectivity and facilitates chelation-assisted coupling, while the methyl substituent provides steric and electronic modulation. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis of functionalized biaryls and heterocyclic scaffolds in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: