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CS-W001157 4
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Exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane

  • CAS No. 76272-36-1

  • Cat. No. CS-0022861
  • Purity≥95%
  • MDL No.MFCD09753144

*For research and further manufacturing use only, not for direct human use.

Exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane|CS-0022861

Structure of 76272-36-1

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General Information

  • CAS No. 76272-36-1
  • Cat. No. CS-0022861
  • Purity ≥95%
  • MDL No. MFCD09753144
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀N₂
  • Molecular Weight 216.32
  • Synonym(s) 8-Benzyl-8-azabicyclo[3.2.1]octane-3-exo-amino
  • SMILES N[C@@H]1C[C@@H](CC[C@H]2C1)N2CC3=CC=CC=C3

Synthesis

  • Route1
    • 8-Benzyl-8-azabicyclo[3.2.1]octan-3-one oxime|CS-M0613
      76272-34-9
    • ~65%
    • Exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane|CS-0022861
      76272-36-1

    References

    • Bagley; Riley Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 3 p. 485 - 488
  • Route2
    • null|null
      132259-54-2
    • ~99%
    • Exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane|CS-0022861
      76272-36-1

    References

    • Asano, Shigehiro; Gavrilyuk, Julia; Burton, Dennis R.; Barbas, Carlos F. ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 2 p. 133 - 137
  • Route3
    • 8-Methyl-8-azabicyclo[3.2.1]octan-3-one oxime|CS-0756891
      1515-26-0
    • ~80%
    • Exo-3-amino-8-benzyl-8-azabicyclo[3.2.1]octane|CS-0022861
      76272-36-1

    References

    • Dostert; Imbert; Langlois; et al. European Journal of Medicinal Chemistry, 1984 , vol. 19, # 2 p. 105 - 110

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.26
  • LogP   2.1407
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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