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Structure of 763114-26-7
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This fluoro-substituted phthalazinylbenzoic acid integrates a sterically hindered dihydrophthalazine core with a strategically positioned carboxylic acid, enabling direct conjugation in bioconjugation workflows. The electron-deficient aryl system enhances reactivity in nucleophilic substitution cascades, while the bench-stable scaffold supports modular derivatization under mild conditions.
2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid serves as a versatile building block for phthalazinone-based pharmaceutical scaffolds. The carboxylic acid group enables direct derivatization via amide coupling or esterification, while the fluoro substituent provides enhanced metabolic stability and modulates electronic properties. The dihydrophthalazinone core offers a rigid, planar structure suitable for target binding interactions. This compound exhibits bench stability and compatibility with standard synthetic workflows, facilitating integration into medicinal chemistry campaigns targeting kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: