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CS-W001157 4
Total: USD 88.00

2-Hydroxypalmitic acid

  • CAS No. 764-67-0

  • Cat. No. CS-0138075
  • Purity≥95%
  • MDL No.MFCD00014343

*For research and further manufacturing use only, not for direct human use.

2-Hydroxypalmitic acid|CS-0138075

Structure of 764-67-0

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General Information

  • CAS No. 764-67-0
  • Cat. No. CS-0138075
  • Purity ≥95%
  • MDL No. MFCD00014343
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₃₂O₃
  • Molecular Weight 272.42
  • Synonym(s) None
  • SMILES CCCCCCCCCCCCCCC(O)C(O)=O

Description

2-Hydroxypalmitic acid features a hydroxyl group at the C-2 position of a saturated 16-carbon chain, enhancing its polarity and hydrogen-bonding capacity. This structural motif imparts distinct solubility characteristics and reactivity in lipid-based systems, enabling use in surfactant design, emulsion stabilization, and biochemical synthesis.

Application

2-Hydroxypalmitic acid serves as a valuable building block in lipid chemistry and surfactant synthesis, offering a hydroxyl group at the β-position for selective derivatization. Its saturated C16 chain provides structural rigidity and hydrophobic character, enabling applications in emulsification, pharmaceutical excipients, and metabolic pathway studies. The molecule exhibits bench stability and facilitates straightforward purification via recrystallization or chromatography, making it well-suited for reproducible laboratory-scale syntheses.

Synthesis

  • Route1
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      260055-66-1
    • ~%
    • In-stock
      2-Hydroxypalmitic acid|CS-0138075
      764-67-0

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 1 p. 63 - 66
  • Route2

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 1 p. 63 - 66
  • Route3
    • 2-Aminohexadecanoic acid|CS-0331074
      7769-79-1
    • ~%
    • In-stock
      2-Hydroxypalmitic acid|CS-0138075
      764-67-0

    References

    • Organic letters, , vol. 2, # 3 p. 347 - 350

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   4.5231
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   14

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