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Structure of 765916-91-4
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2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile delivers a fluorinated aryl boronate moiety with enhanced stability and compatibility in Suzuki-Miyaura coupling reactions. The tetramethyl-substituted dioxaborolane group ensures excellent shelf life and moisture tolerance, while the para-fluoro and nitrile functionalities enable precise electronic tuning in complex molecule assembly. This reagent integrates seamlessly into late-stage functionalization workflows.
2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile serves as a versatile boronate ester building block in Suzuki-Miyaura cross-coupling reactions. The nitrile and fluorine substituents provide orthogonal functionalization handles and enhanced metabolic stability, while the tetramethyl-substituted dioxaborolane offers excellent bench stability and compatibility with diverse reaction conditions. This compound enables efficient construction of biaryl scaffolds common in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: