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CS-W001157 4
Total: USD 88.00

1-Iodo-3-methoxybenzene

  • CAS No. 766-85-8

  • Cat. No. CS-W012919
  • Purity≥98%
  • MDL No.MFCD00001048
  • HazMat Fee +

    HazMat Fee

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-Iodo-3-methoxybenzene|CS-W012919

Structure of 766-85-8

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Description

1-Iodo-3-methoxybenzene features a methoxy group ortho to iodine, enabling selective cross-coupling reactions. This bench-stable aryl iodide integrates efficiently into Suzuki and Negishi protocols, delivering high yields under standard conditions. The electron-donating methoxy substituent enhances reactivity while maintaining stability during handling and storage.

Application

1-Iodo-3-methoxybenzene serves as a versatile aryl halide building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The meta-methoxy substitution provides predictable electronic modulation and enhances solubility, while the iodine handle ensures high reactivity under standard coupling conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate reliable synthesis of complex molecular scaffolds in medicinal chemistry and materials science applications.

General Information

  • CAS No. 766-85-8
  • Cat. No. CS-W012919
  • Purity ≥98%
  • MDL No. MFCD00001048
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇IO
  • Molecular Weight 234.03
  • Synonym(s) Benzene, 1-iodo-3-methoxy-; 1-Iodo-3-methoxybenzene
  • SMILES COC1=CC(I)=CC=C1

Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.2998
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P330-P501

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