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Structure of 766-85-8
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1-Iodo-3-methoxybenzene features a methoxy group ortho to iodine, enabling selective cross-coupling reactions. This bench-stable aryl iodide integrates efficiently into Suzuki and Negishi protocols, delivering high yields under standard conditions. The electron-donating methoxy substituent enhances reactivity while maintaining stability during handling and storage.
1-Iodo-3-methoxybenzene serves as a versatile aryl halide building block in palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl architectures. The meta-methoxy substitution provides predictable electronic modulation and enhances solubility, while the iodine handle ensures high reactivity under standard coupling conditions. Its bench-stable nature and compatibility with diverse functional groups facilitate reliable synthesis of complex molecular scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: