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Structure of 7661-55-4
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5-Methylquinoline is a heterocyclic compound featuring a methyl group at the 5-position of the quinoline core. This substitution enhances electron density at the aromatic system, improving reactivity in electrophilic functionalization. The molecule exhibits good solubility in organic solvents and demonstrates stability under standard bench conditions, making it suitable for use in synthetic transformations and as a ligand in transition metal catalysis.
5-Methylquinoline serves as a versatile heterocyclic building block in medicinal chemistry and catalysis, offering a robust scaffold for drug discovery and ligand design. Its methyl substituent enhances metabolic stability and modulates electronic properties, enabling efficient transition-metal-catalyzed cross-coupling reactions. The compound exhibits excellent bench stability, facilitates straightforward purification, and functions effectively in C–H functionalization and Pd-catalyzed transformations.
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GHS Pictogram :
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GHS No : GHS06,GHS08,GHS09
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H312-H315-H319-H341-H350-H411
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Precautionary Statements : P264-P273-P280
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Lot numbers can be found on the outside label of a product: