Pyrazolo[1,5-a]pyridin-2-ylmethanol

Name: Pyrazolo[1,5-a]pyridin-2-ylmethanol
Brand: ChemScene
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CAS No. 76943-47-0
Cat. No. CS-0270744
Purity≥96%
MDL No.None

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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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Pyrazolo[1,5-a]pyridin-2-ylmethanol|CS-0270744

Structure of 76943-47-0

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Description

Pyrazolo[1,5-a]pyridin-2-ylmethanol integrates a rigid heterocyclic core with a reactive benzylic alcohol, enabling direct functionalization in medicinal chemistry. This bench-stable scaffold supports efficient derivatization for kinase inhibitors and targeted therapeutics.

Application

Pyrazolo[1,5-a]pyridin-2-ylmethanol serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds. Its benzylic alcohol functionality facilitates direct functionalization—such as oxidation to carboxylic acids or conversion to esters and amides—while maintaining compatibility with common protecting group strategies. The rigid, electron-deficient core supports diverse coupling reactions and offers favorable physicochemical properties for drug discovery applications.

General Information

CAS No. 76943-47-0
Cat. No. CS-0270744
Purity ≥96%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₈N₂O
Molecular Weight 148.16
Synonym(s) 2-hydroxymethylpyrazolo[1,5-a]pyridine
SMILES C1=CC2=CC(=NN2C=C1)CO

Computational Chemistry Data

TPSA 37.53
LogP 0.8266
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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Pyrazolo[1,5-a]pyridin-2-ylmethanol

CAS No. 76943-47-0

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