Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-4-methylbenzoic acid

  • CAS No. 7697-23-6

  • Cat. No. CS-W002990
  • Purity≥98%
  • MDL No.MFCD03092906

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-methylbenzoic acid|CS-W002990

Structure of 7697-23-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 7697-23-6
  • Cat. No. CS-W002990
  • Purity ≥98%
  • MDL No. MFCD03092906
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇FO₂
  • Molecular Weight 154.14
  • Synonym(s) Benzene, 1,2,3,4,5-pentafluoro-6-methyl-
  • SMILES Cc1ccc(c(c1)F)C(=O)O

Description

2-Fluoro-4-methylbenzoic acid features a strategically positioned fluorine atom and methyl group on the aromatic ring, enabling enhanced metabolic stability and targeted electronic effects. This ortho-fluorinated benzoic acid derivative integrates readily into pharmaceutical scaffolds, offering improved lipophilicity and binding affinity in bioactive molecule design.

Application

2-Fluoro-4-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-methyl substituents provide predictable electronic modulation and enhanced metabolic stability. The carboxylic acid group facilitates direct coupling reactions, while the molecule exhibits excellent bench stability and compatibility with standard functional group manipulations.

Synthesis

  • Route1
    • null|null
      352-70-5
    • In-stock
      Potassium tert-butoxide|CS-0864415
      865-47-4
    • ~44%
    • In-stock
      2-Fluoro-4-methylbenzoic acid|CS-W002990
      7697-23-6

    References

    • Munson, Mark; Rizzi, James; Rodriguez, Martha; Kim, Ganghyeok Patent: US2004/176325 A1, 2004 ; Location in patent: Page/Page column 31; sheet 33 ; US 20040176325 A1
  • Route2
    • null|null
      124-38-9
    • In-stock
      1-Bromo-2-fluoro-4-methylbenzene|CS-W008820
      452-74-4
    • ~36%
    • In-stock
      2-Fluoro-4-methylbenzoic acid|CS-W002990
      7697-23-6

    References

    • Zou, Xinzhuo; Qiu, Zongxing Journal of Fluorine Chemistry, 2002 , vol. 116, # 2 p. 173 - 179
  • Route3

    References

    • Journal of Fluorine Chemistry, , vol. 116, # 2 p. 173 - 179

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.83232
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Fluoro-4-methylbenzoic acid sigma2-Fluoro-4-methylbenzoic acid manufacturer2-Fluoro-4-methylbenzoic acid price2-Fluoro-4-methylbenzoic acid structure2-Fluoro-4-methylbenzoic acid SDSbuy 2-Fluoro-4-methylbenzoic acid2-Fluoro-4-methylbenzoic acid supplier2-Fluoro-4-methylbenzoic acid uses2-Fluoro-4-methylbenzoic acid molecular weightprice of 2-Fluoro-4-methylbenzoic acid2-Fluoro-4-methylbenzoic acid chemical name formula of 2-Fluoro-4-methylbenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label