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Structure of 77112-53-9
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Imidazo[1,2-a]pyrazine-2-carboxylic acid features a fused heterocyclic core with dual nitrogen-rich rings and a carboxylic acid handle at the 2-position. This scaffold delivers enhanced solubility and metabolic stability, enabling direct integration into bioactive molecule design. The electron-deficient framework supports efficient coupling reactions and serves as a privileged pharmacophore in medicinal chemistry.
Imidazo[1,2-a]pyrazine-2-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard amide coupling and derivatization protocols. The carboxylic acid functionality facilitates direct conjugation with amines, while the fused imidazo[1,2-a]pyrazine core provides structural rigidity and enhanced metabolic stability. Bench-stable and compatible with common purification methods, it functions effectively in parallel synthesis campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: