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Structure of 77150-35-7
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8-Bromoquinazolin-4(1H)-one is a bench-stable, electron-deficient heterocycle featuring a bromine substituent at the C8 position. This strategic halogenation enables direct functionalization in cross-coupling reactions, while the quinazolinone core provides a rigid scaffold for medicinal chemistry applications.
8-Bromoquinazolin-4(1H)-one serves as a versatile scaffold for medicinal chemistry campaigns, enabling direct incorporation into kinase inhibitor and bioactive heterocycle libraries. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the quinazolinone core exhibits favorable stability and solubility for downstream functionalization. The compound functions reliably in standard synthetic workflows, offering predictable reactivity and ease of purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: