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CS-W001157 4
Total: USD 88.00

Ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate

  • CAS No. 77156-78-6

  • Cat. No. CS-W012683
  • Purity≥96%
  • MDL No.MFCD00085617

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate|CS-W012683

Structure of 77156-78-6

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General Information

  • CAS No. 77156-78-6
  • Cat. No. CS-W012683
  • Purity ≥96%
  • MDL No. MFCD00085617
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₃NO₄
  • Molecular Weight 247.25
  • Synonym(s) ethyl 6-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylate
  • SMILES CCOC(=O)C1=C(O)C2=C(C=CC(OC)=C2)N=C1

Synthesis

  • Route1
    • 2-((4-Methoxyphenylamino)Methylene)Malonic Acid Diethyl Ester|CS-0038351
      83507-70-4
    • ~73%
    • In-stock
      Ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate|CS-W012683
      77156-78-6

    References

    • GLAXO GROUP LIMITED Patent: WO2006/2047 A2, 2006 ; Location in patent: Page/Page column 60 ;
  • Route2
    • null|null
      104-94-9
    • In-stock
      Diethyl 2-(ethoxymethylene)malonate|CS-0019402
      87-13-8
    • ~75%
    • In-stock
      Ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate|CS-W012683
      77156-78-6

    References

    • GLAXO GROUP LIMITED Patent: WO2006/14580 A1, 2006 ; Location in patent: Page/Page column 38 ;
  • Route3
    • null|null
      142892-71-5
    • ~44%
    • In-stock
      Ethyl 4-hydroxy-6-methoxyquinoline-3-carboxylate|CS-W012683
      77156-78-6

    References

    • Tsunoda, Hidetoshi; Fukazawa, Nobuyuki; Nagase, Hiroshi; Chiba, Kyoko; Nakao, Toshifumi; Asada, Noriaki; Yamaki, Toshifumi; Kibayashi, Kenji; Migita, Hideyuki; Morikawa, Maki Patent: US2003/212100 A1, 2003 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   68.65
  • LogP   2.1257
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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