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CS-W001157 4
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2,4,6-Trimethylpyrylium tetrafluoroborate

  • CAS No. 773-01-3

  • Cat. No. CS-0326417
  • Purity≥97%
  • MDL No.MFCD00032098

*For research and further manufacturing use only, not for direct human use.

2,4,6-Trimethylpyrylium tetrafluoroborate|CS-0326417

Structure of 773-01-3

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General Information

  • CAS No. 773-01-3
  • Cat. No. CS-0326417
  • Purity ≥97%
  • MDL No. MFCD00032098
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BF₄O
  • Molecular Weight 209.98
  • Synonym(s) Pyrylium, 2,4,6-trimethyl-, tetrafluoroborate(1-)
  • SMILES CC1=CC(C)=[O+]C(C)=C1.F[B-](F)(F)F

Description

This pyrylium salt features a highly electrophilic ring stabilized by three methyl groups, enhancing solubility and reactivity. The tetrafluoroborate counterion ensures excellent stability and compatibility with polar solvents. Designed for efficient arylation and cyclization reactions in synthetic organic chemistry workflows.

Application

2,4,6-Trimethylpyrylium tetrafluoroborate serves as a highly reactive electrophilic synthon in organic synthesis, enabling efficient alkylation of nucleophiles under mild conditions. Its stability and solubility facilitate straightforward handling and purification, while the trimethyl substitution enhances regioselectivity in heterocyclic functionalization. Widely used in the construction of substituted pyrylium salts and related scaffolds, it functions reliably in standard bench-scale transformations.

Synthesis

  • Route1
    • null|null
      123-42-2
    • null|null
      108-24-7
    • ~72%
    • In-stock
      2,4,6-Trimethylpyrylium tetrafluoroborate|CS-0326417
      773-01-3

    References

    • Bulletin de la Societe Chimique de France, , # 1 p. 205 - 211
  • Route2
    • null|null
      108-24-7
    • null|null
      75-65-0
    • ~24%
    • In-stock
      2,4,6-Trimethylpyrylium tetrafluoroborate|CS-0326417
      773-01-3

    References

    • Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 43, # 6 p. 565 - 583
  • Route3
    • In-stock
      3,5-Di-tert-butyl-o-benzoquinone|CS-0095759
      3383-21-9
    • null|null
      108-24-7
    • ~54%
    • In-stock
      2,4,6-Trimethylpyrylium tetrafluoroborate|CS-0326417
      773-01-3

    References

    • Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 19, # 4 p. 364 - 368 Khimiya Geterotsiklicheskikh Soedinenii, , # 4 p. 454 - 458

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   11.3
  • LogP   3.78596
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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