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Structure of 773134-49-9
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Methyl 7-methyl-1H-indole-3-carboxylate features a sterically hindered indole core with a methyl group at the 7-position, enhancing metabolic stability. The ester functionality enables direct use in cross-coupling reactions and facilitates downstream derivatization. This bench-stable compound serves as a key building block for bioactive heterocycles in medicinal chemistry and materials science.
Methyl 7-methyl-1H-indole-3-carboxylate serves as a versatile building block in heterocyclic synthesis, offering a readily accessible indole scaffold with orthogonal functional handles. The methyl ester group enables straightforward derivatization via hydrolysis or reduction, while the 7-methyl substituent enhances electronic stability and facilitates electrophilic substitution at C-6. Its bench-stable nature and compatibility with palladium-catalyzed cross-coupling reactions make it a practical choice for constructing complex indole-based architectures in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: